‘Dragon Man’ skull may be the first from an enigmatic human cousin
Ancient proteins and DNA may peg a 146,000-year-old Chinese skull as the most complete fossil to date from Denisovans, a puzzling line of Asian hominids.

Meet the new face, and braincase to boot, of Asia’s mysterious Stone Age denizens, the Denisovans.
The on the self-discipline of full, roughly 146,000-365 days-dilapidated cranium of an adult male became as soon as chanced on on the self-discipline of a century ago, most definitely at some stage in bridge construction in Harbin, China. An earlier seek for claimed that the Harbin cranium, nicknamed Dragon Man, represented a new species known as Homo longi. Two new study now argue it is miles, as an different, the most important-ever cranium from a Denisovan inhabitants — even supposing scientists no longer desirous about the new investigations disagree on whether or no longer ample evidence exists to substantiate Dragon Man’s evolutionary id.
Researchers before every thing acknowledged Denisovans in 2012 in line with DNA extracted from a fossil finger fragment chanced on in a Siberian cave and labeled these Asian hominids as shut Neandertal relatives. Nonetheless scientists may maybe no longer state what Denisovans regarded love in line with a partial finger bone. Since then, handiest a handful of Denisovan fossils occupy turned into up, along side a partial lower jaw and a rib.
“Here's the most important time we occupy got linked a [fossil] cranium to Denisovans,” says evolutionary geneticist Qiaomei Fu of the Institute of Vertebrate Paleontology and Paleoanthropology, or IVPP, in Beijing.
Fu’s crew makes a case for having cornered the most important Denisovan cranium in two programs. Outmoded proteins extracted from the Harbin fossil negate a molecular makeup that links them to old examples of Denisovan proteins, the scientists state June 18 in Science.
Analyses of proteins in attach-day other folks and great apes, Neandertals and Denisovans uncovered three protein variants chanced on handiest in Denisovans. Those variants furthermore looked within the Harbin cranium. Proteins extracted from the Chinese cranium that displayed chemical signs of novel contamination, most definitely by the burial atmosphere or human facing, were excluded.
In lend a hand of the protein findings, mitochondrial DNA got from the Chinese cranium’s dental tartar carefully align with that of quite a lot of Denisovans from southern Siberia’s Denisova Cave, the investigators function June 18 in Cell. Since young other folks in general inherit mitochondrial DNA from the mummy, the new genetic evidence suggests that Denisovans with a shared maternal ancestry ranged from Central to East Asia, the researchers state.
Unlike mitochondrial DNA, proteins — which lend a hand greater in fossils than genes catch — provide clues to the inheritance of nuclear DNA from both other folks. Investigators previously reported having detected Denisovan proteins in a fossil from Central Asia’s Tibetan Plateau dubbed the Xiahe jaw and in a single other jaw known as Penghu 1 chanced on off Taiwan’s waft.
“The extraction of feeble proteins and feeble DNA from the Harbin cranium extra confirms that Denisovans were broadly allotted in Asia at some stage within the Heart Pleistocene,” says IVPP paleoanthropologist Xiujie Wu, who didn't participate within the new study. The Heart Pleistocene refers to a pivotal interval of Homo evolution that ran from about 789,000 to 130,000 years ago.
Fancy Wu, paleoanthropologist Yousuke Kaifu of the College of Tokyo sees Dragon Man as part of a Denisovan inhabitants that spread over a monumental swath of Asia. “If we regard Neandertals as a undeniable species, then why no longer Denisovans,” Kaifu says.
Nonetheless IVPP paleoanthropologist Xijun Ni, who became as soon as no longer part of Fu’s team, is rarely any longer willing to proclaim the Harbin cranium a Denisovan. Researchers need an even bigger sample of feeble protein variants to discover whether or no longer the Chinese obtain, as effectively as Taiwan’s Penghu 1 jaw, qualifies as Denisovan, Ni says.
As an instance, the 2 protein variants dilapidated to categorise Penghu 1 as Denisovan may as an different attain from an feeble Homo sapiens that most definitely inherited some Denisovan genes through interbreeding, evolutionary biologists Derek Taylor and Victor Albert, both of the College at Buffalo in New York, wrote in a May 5 eLetter printed in Science.
Ni, who led the team that labeled the Harbin cranium as H. longi, furthermore suspects that Fu’s crew studied mitochondrial DNA containing up-to-the-minute contaminants. Tartar on enamel surfaces of the Chinese cranium has been touched repeatedly by collectors, researchers and technicians whose DNA got incorporated into the hardened plaque, Ni says.
Despite screening details to reconstruct feeble mitochondrial DNA, “the authors may maybe occupy definitely recovered many DNA fragments from me attributable to I studied and handled the [skull] so repeatedly,” Ni says.
Fu and colleagues failed in attempts to extract DNA from the Harbin cranium’s petrous bone, an inner ear bone that preserves genetic cloth in particular effectively, or from enamel enamel unexposed to human contact.
So for now, Denisovans tranquil take care of essential of their mystery.
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